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| Chanllergen - Dermatophagoides Farinae Drops
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Indications
Mite induced allergic rhinitis and allergic asthma.
Besides, we have fini-
shed the preclinical trial data indicate that the drug may be effective to atopic dermatitis and atopic conjunctivitis, the application of relative
clinical trial is under approval.
Storage
Different from most protein products which should be stored in cold condition, Chanllergen ¨C Dermatophagoides drops could be stored in
room temperature thanks to the patent stabilizing technology. This
obvious advantage could bring convenience to patients for their routine drug administration even they have to stay outside.
How does it work?
Allergy is caused by an oversensitive immune system, which leads to a misdirected
immune response. The immune system reacts to allergens that are generally harm
less and in most people do not cause a problem.
Dermatophagoides Farinae Drops applies sublingual immunotherapy to treat and
may even cure the mite induced allergic diseases.
How to use it?
The drug should be used under a physician's supervision.
There are five specifications with different concentrations of the drug, with respective name as Dermatophagoides Farinae Drops No.1, No.2, No.3,No.4 and N-
o.5.
Take the drug once a day at fixed interval, when apply drops under
the tongue, hold for at least one minute and then swallow. General dosages of the drug are shown in
the following tables. It is recommen-
ded to keep using the drug for at least 2 years.
(click image for larger view)
The dosage could be adjusted by professional physicians according to the individual
degree of allergy.
Efficacy
The clinical indications variation before and after the treatment in test and control groups
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Test group |
Control group |
Pvalue |
| The day PEF variation (L/min) |
31.69¡À3.66 |
17.48¡À3.50 |
0.0039 |
| The night PEF variation (L/min) |
28.64¡À3.63 |
19.03¡À3.46 |
0.0485 |
| Daily PEF change (%) |
-3.48¡À0.29 |
-2.67¡À0.28 |
0.0381 |
| The change of asthma score in day-time (%) |
-0.61¡À0.67 |
-0.72¡À0.79 |
0.3558 |
| The change of asthma score in night-time (%) |
-0.91¡À0.83 |
-0.87¡À0.77 |
0.7556 |
| FEV1 variation (L) |
0.13¡À0.50 |
0.09¡À0.38 |
0.4755 |
| The percentage of FEV1 in forecasted number |
-0.65¡À35.86 |
-4.29¡À37.52 |
0.2154 |
| The change of quick-relief medication (%) |
-0.08¡À1.78 |
0.51¡À1.74 |
0.0148 |
Chanllergen in market
Since it was launched into Chinese pharmaceutical market, Chanllergen-Dermatophagoides Farinae Drops has been helping tens of thousands of patients. It has
been accepted by hundreds of famous hospitals and been proved to be efficacious
and safe.
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